The book describes the fundamental principles of HyFlex design, explains a process for design and development, and discusses implementation factors that instructors, designers, students and administrators have experienced in a wide variety of higher education institutions; public and private, larger and small, research-intensive, comprehensive and community colleges. These factors include the drivers, the variations in implementation approaches and constraints, and the results (e.g., student success metrics, student satisfaction). A series of worksheets in Chapter 1.4 provides specific guidance that can be used by individuals or teams engaging in HyFlex design projects at their own institution. Case reports in Unit III from institutions and faculty who have successfully implemented HyFlex-style courses provide a rich set of real-world stories to draw insights for a reader’s own design setting.